It also causes a release of chemicals in the brain that can cause inflammation swelling and irritation. Sumatriptan works by helping to bring your blood vessels back to their normal size.
If these effects are mild, they may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:. Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.
This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Sumatriptan oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Do not take these drugs with sumatriptan. Doing so can cause dangerous effects in the body. Examples of these drugs include:. Side effects from sumatriptan: Taking sumatriptan with certain medications raises your risk of side effects from sumatriptan. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions.
Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. If you have an allergic reaction, call your doctor or local poison control center right away.
If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death. For people with heart conditions: Sumatriptan may cause serious problems with your heart. Also tell them if you have any other heart condition, such as coronary artery disease CAD or angina chest pain.
If you have any of these conditions, you should not use this drug. Your doctor will find other options to treat your symptoms of migraine. For people with heart rhythm disorders: Sumatriptan may cause changes in your heart rhythm. Tell your doctor if you have any heart rhythm disorders. If you have certain types of heart rhythm disorders, you should not use this drug.
For people with a previous stroke or mini-stroke: This drug may cause severe bleeding in the brain brain hemorrhage or stroke. For people with problems with circulation: Sumatriptan may cause or worsen symptoms of a condition called peripheral vascular disease. If you have this condition, you should not use this drug. For people with serious bowel disorders: Sumatriptan may cause or worsen symptoms of a condition called ischemic bowel disease.
If you have this condition, talk with your doctor about whether this drug is safe for you. For people with uncontrolled high blood pressure: Sumatriptan can increase your blood pressure. For people with serious liver disease: You should not use sumatriptan. For people with seizures: Sumatriptan may cause seizures. For pregnant women: Research in animals has shown negative effects to the fetus when the mother takes the drug.
However, studies done in humans have not shown negative effects to the fetus. This drug should be used only if the potential benefit justifies the potential risk to the fetus. For women who are breastfeeding: Sumatriptan may pass into breast milk and may cause side effects in a child who is breastfed. You should not breastfeed your child for at least 12 hours after taking sumatriptan. Talk to your doctor if you breastfeed your child. Although not all of these side effects may occur, if they do occur they may need medical attention.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Other side effects not listed may also occur in some patients.
If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. There is a problem with information submitted for this request. Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health. Error Email field is required. On rare occasions, these sensations could be symptoms of heart problems, such as a heart attack.
Nausea is a common symptom of migraine. Some people find that taking Imitrex helps reduce the nausea that they have with their migraine, as well relieving the headache.
But some people may have nausea as a side effect of taking Imitrex. In clinical studies , people who used the Imitrex nasal spray had slightly more nausea than those who used a placebo a treatment containing no active drug. This could be because the Imitrex nasal spray can cause an unpleasant taste in your mouth. If you have nausea with Imitrex, talk with your doctor.
They may be able to suggest ways to relieve this side effect. Typically, your doctor will start you on a low dosage. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. The following information describes dosages that are commonly used or recommended.
However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. You should only take it if you get a migraine or cluster headache. Imitrex tablets are available in strengths of 25 milligrams mg , 50 mg, and mg. The tablets are taken by mouth. The Imitrex nasal spray comes in strengths of 5 mg and 20 mg. The nasal spray device contains a single dose that you spray into one nostril only.
Cartridges for the pen come in strengths of 4 mg and 6 mg. The Imitrex vial is available in a strength of 6 mg. It contains a single dose of liquid solution for use with a syringe. To treat migraine with Imitrex tablets taken by mouth, your doctor may prescribe a dose of 25 mg, 50 mg, or mg. The second dose should be taken at least 2 hours after your first dose.
Imitrex tablets may also be used if your migraine returns after an initial Imitrex injection. To treat migraine with Imitrex nasal spray, your doctor may prescribe a dose of 5 mg, 10 mg, or 20 mg.
To treat a migraine attack, your doctor may prescribe a dose of 1 mg to 6 mg of Imitrex given by subcutaneous injection. This is an injection under the skin.
Other doses will need to be given by syringe using liquid solution from a vial. The second dose should be taken at least 1 hour after your first dose. Only the Imitrex injection is used to treat cluster headaches.
The recommended dosage for this use is 6 mg, given by subcutaneous injection. You can take Imitrex to treat up to four migraine or cluster headaches a month. This could mean taking Imitrex 4 days in a row or spread out throughout the month.
Taking medication to treat headaches too often can actually make your headaches worse. It can lead to medication overuse headache, which is also called rebound headache.
This occurs when you get headaches more often than usual from taking your medication too often. If you have frequent migraine attacks or cluster headaches, talk with your doctor about ways to prevent them.
If you have migraine attacks or cluster headaches more than four times a month, talk with your doctor about ways to prevent them. Imitrex is FDA-approved to treat migraine. The Imitrex injection is also FDA-approved to treat cluster headaches. Migraine causes a severe, throbbing headache that can last several hours or even days. Cluster headaches happen over a few days, weeks or months, and are usually followed by periods without headaches.
Migraine and cluster headaches are more than just severe headaches. They are neurological conditions that affect certain blood vessels and nerves in the brain. However, with both conditions, headaches happen due to widening or swelling of blood vessels in the brain. Triptans like Imitrex work by stimulating serotonin receptors docking stations found on blood vessels in the brain. This causes these blood vessels to narrow, which helps relieve the migraine or cluster headache.
Imitrex may also block activity in the trigeminal nerve. This is the nerve that allows you to feel sensation in your head and face. Imitrex also relieves symptoms associated with migraine, such as nausea and sensitivity to light and sound.
How long it takes Imitrex to start working depends on the form you take. However, most people find their migraine or cluster headache is much improved within 2 hours of taking a dose. Imitrex tablets typically start to work within 30 minutes, while the nasal spray can start to work in about 15 minutes. Both forms can take up to 2 hours to have their full effect.
The Imitrex injection can start working within 5 to 10 minutes. It usually reaches its full effect within 1 hour. Imitrex will work for a few hours after you take a dose. However, its effect will gradually lessen as the drug is broken down by your body.
It can take about 10 to 12 hours before Imitrex is fully out of your system. Narcotics are strong, opioid-based pain relievers, such as morphine. NSAIDs are pain relievers, such as ibuprofen , that reduce inflammation swelling. Imitrex is a type of drug called a triptan. It narrows swollen blood vessels in the brain.
Unlike narcotics and NSAIDs, it only relieves the pain associated with migraine or cluster headaches. Controlled substances are drugs that have a high potential for being misused. They also have a high risk for people becoming dependent on the drug. This means your body needs the drug to feel normal. Because of these risks, there are special rules around how controlled substances are prescribed and dispensed.
However, if you take Imitrex too often, it can lead to medication overuse headache. This is also called a rebound headache. A medication overuse headache occurs when taking too much Imitrex causes you to get migraine or cluster headaches every day, or more often than usual. It can lead to a cycle of taking extra Imitrex to relieve these headaches, which in turn causes more headaches. Talk with your doctor if you find you need to take it more often than that.
Your doctor can help you break the cycle of medication overuse. They may also recommend ways to help prevent migraine. Some people may find that blood thinners such as warfarin Coumadin help relieve their migraines. However, taking too much Imitrex or taking it too often could make your headaches worse.
This can lead to medication overuse rebound headaches. When this occurs, you get migraine or cluster headaches every day, or more often than usual. In rare cases, taking Imitrex can cause serious side effects that could seem like your migraine or cluster headache is getting worse.
These serious side effects include bleeding in your brain and very high blood pressure. If your headache gets worse after taking a dose of Imitrex, call your doctor right away.
You should check with your doctor about taking Imitrex before surgery. Imitrex works by narrowing your blood vessels, and it can sometimes cause changes to your blood pressure. This could be dangerous during surgery. Talk with your doctor if you have a surgery scheduled. They can tell you if you should stop taking Imitrex in the days before the surgery. You may take Imitrex with certain other drugs to treat or prevent migraine or cluster headaches.
However, you should only take Imitrex with other drugs if your doctor recommends it. These may include:. Taking pain relievers of any kind too often can lead to medication overuse headache.
This occurs when you have migraines or cluster headaches every day, or more often than usual. If you use pain relievers to treat migraine or cluster headaches 10 or more days a month, talk with your doctor. If you have nausea with your migraine, your doctor may recommend taking nausea medications, such as:. If you get frequent migraine or cluster headaches, your doctor may prescribe medication that you take on a regular basis to help prevent headaches.
Examples of medications you may take to prevent migraine or cluster headaches include:. Other drugs are available that can treat your condition.
Some may be a better fit for you than others. They can tell you about other medications that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions. You may wonder how Imitrex compares with other medications that are prescribed for similar uses. Here we look at how Imitrex and Maxalt are alike and different. Imitrex and Maxalt are both FDA-approved to treat migraine with or without aura in adults.
Maxalt can also be used in children ages 6 to 17 years. The Imitrex injection is also approved to treat cluster headaches in adults. Neither drug should be used to prevent migraine or cluster headaches.
Maxalt comes as a tablet that you swallow. It also comes as a tablet that dissolves on your tongue, called Maxalt-MLT. With both Imitrex and Maxalt, you take a dose when you have migraine. For adults, if you take one dose and still have migraine symptoms 2 hours later, you can take a second dose.
Imitrex and Maxalt have some similar side effects and others that vary. Below are examples of these side effects. These lists contain examples of the most common mild side effects that can occur with Imitrex, with Maxalt, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Imitrex, with Maxalt, or with both drugs when taken individually. The use of Imitrex and Maxalt in treating migraine has been directly compared in a number of clinical studies.
A review of studies concluded that Maxalt was more effective for treating migraine than Imitrex. People who took Maxalt were more likely to have relief from headache and nausea 2 hours after taking a dose compared with people who took Imitrex.
According to estimates on GoodRx. However, Imitrex taken by nasal spray or injection may cost more than Maxalt. Imitrex and Maxalt are both brand-name drugs. Generic forms of both drugs are available. Imitrex is available as the generic drug sumatriptan, and Maxalt is available as the generic drug rizatriptan.
Generics usually cost less than brand-name drugs.
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